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The weight loss application of semaglutide accelerated after Novo Nordisk launched Wegovy in June 2021, the first GLP-1 explicitly approved by the FDA for chronic weight management in adults

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The most prominent pathogenetic processes in liver and bowel illnesses are oxidative stress (OS) and inflammation, which are recognized to play a vital role in several pathologies such as acetaminophen overdose, ulcerative colitis, Crohn's disease, and non-acetaminophen-induced acute liver failure [57]

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J Immunol 204:16 Wei P, Yang Y, Ding Q, Li X, Sun H, Liu Z et al (2016) Oral delivery of Bifidobacterium longum expressing -melanocyte-stimulating hormone to combat ulcerative colitis