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Table 1 below presents a listing of compounds in Family 1 , drawn to mimetics, and Famillies 2-5, drawn to antagonists, all of which have been synthesized and analyzed according to the procedures described above

However, the widespread adoption of organoid and OoC models remains constrained by technical complexity, reproducibility and standardisation challenges, scalability issues, and evolving regulatory frameworks [177]

Mitragotri, S., Burke, P

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