Many patients report an immediate boost in energy, while metabolic and weight-related effects may take a few weeks to become noticeable
Occasional vomiting , typically associated with rapid dose escalation
Use sunscreen daily and limit sun exposure, as both Azelaic Acid and Tretinoin increase photosensitivity

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1998 Sep 5;352(9130):763-6
This patient has an intense KayserFleischer ring, seen easily with the naked eye