The Navitus Drug Trend Report revealed three critical trends influencing the broader industry: 26% increase in GLP-1 RAs use for treatment of type 2 diabetes
Some lower BMI patients have underlying insulin resistance, prediabetes, or metabolic dysfunction that benefits from GLP-1 receptor activation independent of weight loss
Effects of corticosteroids
high concentrations in organs that require vitamin C as a cofactor (e.g., adrenal gland) Functions Antioxidant: ascorbate and dehydroascorbate form a redox system Can cause false-negative results on stool guaiac test, which is a color-producing oxidant reaction [21] Promotes intestinal iron resorption As chelating agent: increases iron solubility through chelate complex formation As redox partner: reduces poorly soluble Fe 3+ into highly soluble Fe 2+ intestinal absorption Coenzyme for important enzymatic reactions Collagen synthesis: hydroxylation of proline and lysine Noradrenaline synthesis: required for dopamine -hydroxylase (hydroxylation of dopamine to noradrenaline) Carnitine synthesis Peptide hormone synthesis from prehormones (e.g., vasopressin, calcitonin, oxytocin) Think of vitamin C as absorbic acid since it promotes the intestinal absorption of iron
doi: 10.1152/physrev.00034.2006 2 Inflammation
One thing to watch: keep the bar brushing your legs the whole way down