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A commenter noted investing more than $7.5 million over 6+ years for two seminal RCTs, stating such investment in post-FDA studies alone exceeds application fees of both PMA and BLA products but is not captured in CMS' FDA pathway analysis

Growth factors activate fibroblasts and tenocytes at the injury site

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Thereby, BPC 157 effects envisage a balance between competing proangiogenic and antiangiogenic mediators