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Its Innovative Science and Technology Approaches for New Drugs (ISTAND) pilot program is explicitly considering complex in vitro models like OoCs, with a liver-on-chip for DILI being the first OoC accepted into the program for evaluation (222)

There are two main types of volume expander: crystalloids and colloids

Pharmacological alternatives: Prescription antiemetics (for persistent nausea): Metoclopramide : Prokinetic agent that may counteract delayed gastric emptying (short-term use only due to neurological risks)

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Although these occurrences are rare, with the drugs vast user base, it could mean hundreds of thousands of individuals might encounter these complications