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Triumph-3 enrolled 1,949 adults with severe obesity, defined as BMI of 35 kg/m or higher, and established cardiovascular disease, with or without type 2 diabetes

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Identification of the molecular basis of doxorubicin-induced cardiotoxicity

A study in the International journal of Molecular Sciences (2022) later revealed that spermine, another polyamine, suppressed adipocyte differentiation and fat accumulation in mice on high-fat diets, suggesting it could be a potential treatment for obesity

Eur Radiol 2001;11:15631577

Participation of NADPH oxidase-related reactive oxygen species in leptin-promoted pulmonary inflammation: regulation of cPLA2 and COX-2 expression