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Estrogen levels may spike unexpectedly, leading to a thicker-than-usual uterine lining

Tesfamariam, M., Vij, R., Trumper, V., Hube, B

Local inhibition is still fine, because you wont get the systemic/brain inhibition, leading to depression, anxiety, insomnia, overstimulation, sexual dysfunction, etc

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Think of it less like a foreign chemical and more like a copy of a molecule you were born with