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Burlingame, CA) or biotin-conjugated anti-rat IgG antibody (F4/80: Vector Laboratories) in 0.1 M PBS at 22 2 C for 30 min

They are also seen as a key expansion direction for obesity and metabolic disease therapies

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The studies in vivo indicated that the GEN-loaded star-shaped copolymer mannitol-functionalized nanoparticles were able to show significantly superior antitumor activity than the linear copolymer mannitol-functionalized nanoparticles and pristine GEN (Wu et al., 2016)