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G-actin sequestration Primary function, essential for motility of fibroblasts, keratinocytes, endothelial cells and cardiomyocytes

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The initiation of an iron starvation response and ferritinophagy during RANKL stimulation under normoxic conditions suggests that iron and ROS play a critical role in osteoclast differentiation ( Conclusion In summary, research on ferroptosis in osteoporosis is still in its early stages, with most studies conducted in animal models

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