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In addition, it recycles vitamin C, regenerates vitamin E, and reduces the skin erythema induced by UVB [86]

Thymosin alpha-1 levels in people with PsA remained low even when they received treatment with disease-modifying antirheumatic drugs (DMARDs), especially when combined with a corticosteroid

This multidimensional interplay not only explains the selective vulnerability of dopaminergic neurons but also provides a rationale for mitochondria-targeted combination therapies (e.g., mitochondrial-targeted antioxidant SS-31 combined with ferroptosis inhibitors)

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In addition, other studies have also demonstrated the involvement of TRP channels in paclitaxel-induced pain, which are well known to be predominantly expressed on this subpopulation of DRG neurons