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Some people carry genetic variants associated with heightened GLP-1 pathway activation, potentially increasing the likelihood of rapid appetite loss and metabolic adaptationboth contributors to fatigue
Our findings add to growing evidence that GLP-1 medications may influence more than appetite and blood sugar regulation, said Dr Tadesse Abegaz, lead author and researcher at the UTEP School of Pharmacy
HbA1c for the repaglinide-treated groups (1 and 4 mg groups combined) at the end of the study was decreased compared to the placebo-treated group in treatment nave patients and in patients previously treated with oral hypoglycemic agents by 2.1% and 1.7%, respectively
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