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Key Tirzepatide Formulations Mounjaro: FDA-approved for type 2 diabetes management Zepbound: FDA-approved for chronic weight management in adults with BMI 30 or greater, or BMI 27 or greater with a weight-related comorbidity Efficacy Comparison The SURMOUNT-1 trial showed tirzepatide at 15 mg weekly produced average weight loss of 22.5% of body weight at 72 weeks, compared to approximately 15% to 17% with semaglutide 2.4 mg in the STEP trials

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