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This task is more challenging with smaller stomachs (the stomach is 80-90% smaller in the bypass and sleeve) because of the reduced gastric acid volume

But, serious side effects are rare

This is mechanistically novel for the GLP-1 class

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monitoring and diagnosis stopped

The Gastrointestinal Safety of Orforglipron, a GLP-1 Receptor Agonist, in Adults With or Without Type 2 Diabetes: A Network Meta-Analysis of Randomized Controlled Trials