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For OA patients with mechanical overload, correcting the abnormal mechanical environment while performing targeted molecular intervention is expected to more significantly slow cartilage degeneration (Zhang Y

1 Vannelli BG, Barni T, Orlando C, Natali A, Serio M, Balboni GC: Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study

Post-hoc power calculations (G*Power 3.1) using the reported effect sizes (Cohens d 0.250.40) indicate that 80% power to detect a minimal clinically important difference of 1 cm on the VAS pain scale would require 128200 completers per arm

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doi: 10.1126/science.317.5835.190

A: It is categorized as a general medicine