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Weight loss pills can have several disadvantages

The GLP-1 family acts heavily on the gut-brain axis through slowed digestion and reduced hunger signalling

2024 J Control Release

To serve as mucoadhesive polymers, the polymers should possess some general physiochemical features such as predominantly anionic hydrophilicity with numerous hydrogen bond forming groups, suitable surface property for wetting mucus/mucosal tissue surfaces and sufficient flexibility to penetrate the mucus network

Therefore, any human use remains experimental and unapproved

These types of drugs are not recommended for people who have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndromes, specifically types 2A or 2B