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Gain-of-function studies demonstrated that recombinant BDNF mimics might have beneficial effects on NSC transplantation, while loss-of-function studies showed that mice depleted of NSC-derived BDNF failed to improve cognition or restore hippocampal synaptic density (80)

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Phase II Randomized Controlled Trial in Celiac Disease This early human study tested larazotide acetate in people with celiac disease eating gluten or avoiding it

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Make sure that the tip of the needle is in the liquid and slowly pull the plunger down until the plunger tip is past the 0.5 mL line