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In addition, pharmacological intervention with SAHA also restored the histone H3 acetylation level, reversed pathological form of synaptic plasticity, and abrogated the epileptic phenotype in the TSC2 +/ mice showing the neurological manifestations including seizures, autism and cognitive deficits [138]

The unfolded protein response: from stress pathway to homeostatic regulation

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A review of metallothionein isoforms and their role in pathophysiology

Introduction Hair follicles appear already during fetal life

These transporters are responsible for the movement of a wide variety of xenobiotics, including drugs, lipids and metabolic products across plasma and intracellular membranes [ 81 ]