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A role of oxidative stress in GO is supported by a number of basic studies suggesting that ROS promote the proliferation of OFs and the release of GAGs, the synthesis and secretion of cytokines, and the expression of other factors involved in the pathogenesis of GO, namely heat shock protein 72 (HSP-72), HLA-DR and ICAM-1 ( Figure 1 In this context, a number of studies, performed both in vitro and in vivo , investigated the effects of antioxidant agents in GO, including selenium, pentoxifylline, quercetin, enalapril, vitamin C, N-acetyl-L-cysteine and melatonin ( Oxidative Stress and Proliferation of Orbital Fibroblasts Burch et al

Indem es zum Beispiel antioxidativ wirkt, verndert Glutathion den oxidativen Zustand in den Zellen

Compound Type: Modified Pentadecapeptide (BPC-157 analogue with Arginine modification)

18-24 months: Approaching labeled expiration

When these ingredients are combined, they provide a more comprehensive approach to healthy aging and vitality

Lancet 376 , 419430 (2010)