Based on this, it was assumed that 24 evaluable subjects would be required for each of the investigated dosing schedules and 48 evaluable subjects would be required for the reference dosing schedule in order to provide an 80% probability that the 95% CI for the true ratio between groups for AUC 024h,sema,Day10 would fall between 0.75* and 1.34*, where was the unknown estimate of the ratio
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Contemp Clin Trials Commun 28:100944 Minozzi S, Dwan K, Borrelli F, Filippini G (2022) Reliability of the revised Cochrane risk-of-bias tool for randomised trials (RoB2) improved with the use of implementation instruction
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Does PT-141 help men with ED
[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention