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The Supplement Facts label for Vital Blood doesn't list any of the major FDA-recognized allergens (milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soybeans) in the ingredient list

Okumura, R., & Takeda, K

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The latter finding is particularly important, because it reveals that betalains can be absorbed into the systemic circulation in their unchanged form, allowing them to retain their molecular structure and high biological activity [34]

Stress management deserves mention here because stress directly increases stomach acid production and heightens esophageal sensitivity