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In these patients, GLP1RA are likely preferable to SGLT2i if cerebrovascular disease predominates, but both classes can be used together with additional benefits on reducing glucose levels, weight and cardiovascular disease

However, of this cohort with improved EF, 41% had a recurrent decline in LVEF (EF 40%) over a median follow-up of 11 years 18

[Google Scholar] Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site