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This dose-dependent relationship means finding the right balance between efficacy and tolerability becomes critical for long-term success
Tirzepatide (LY3298176) is a first-in-class synthetic peptide that activates two key metabolic hormone receptors at once the GIP (glucose-dependent insulinotropic polypeptide) receptor and the GLP-1 (glucagon-like peptide-1) receptor
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S5a, b)
It also regulates caspase-3 and Bcl-2 proteins to protect neurons from glutamate toxicity, thereby reducing the risk of ischemic stroke and brain damage [22]
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