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Systemic antibodies towards mucosal bacteria in ulcerative colitis and Crohn's disease differentially activate the innate immune response

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Moreover, the program is short-lived

Antibody development was not associated with decreased effectiveness, but it was associated with an increase in hypersensitivity and injection site reactions (6.2% and 11.3%, respectively)

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[DOI] [PubMed] [Google Scholar] 56.Zhang J., Wu Y., Jin Y., Ji F., Sinclair S.H., Luo Y., Xu G., Lu L., Dai W., Yanoff M., et al