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In addition, they found that both the transcript and the protein levels of Nrf2 and the detoxifying/antioxidant enzymes HO1 and NQO1 were significantly decreased [252]

Studies have shown that 70% of Kenyan schoolchildren, 70% of East Indian adults, and 40% of Latin American residents are B12 deficient

Two popular options for supplementation are Vitamin B12 injections and oral supplements

Rolls ET, Grabenhorst F

All participants were 18 years or older, planned to initiate HCV antiviral treatment, and provided signed informed consent documents to participate in a single-center, open-label study (ClinicalTrials.gov Identifier: NCT02734173), which was approved by The Ottawa Health Science Network Research Ethics Board (REB 2015-0305)

doi: 10.1111/dom.13506 42 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al