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In the UK, the storage and handling of licensed medicines is governed primarily by the Medicines and Healthcare products Regulatory Agency (MHRA) , with clinical guidance on specific therapeutic areas provided by the National Institute for Health and Care Excellence (NICE) and the NHS

The therapeutic efficacy of these GSH-responsive platforms depends on the extent to which intracellular GSH levels are sufficiently elevated and spatially restricted within tumor cells relative to surrounding normal tissues

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10.1016/j.ijcard.2013.07.190 85

Calcif Tissue Int (2015) 97(2):10412.10.1007/s00223-015-9993-5 21 DriessenJHvan OnzenoortHAStarup-LindeJHenryRBurdenAMNeefCet alUse of glucagon-like-peptide 1 receptor agonists and risk of fracture as compared to use of other anti-hyperglycemic drugs

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