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Overall, both surgical and medical treatments face limitations such as high recurrence rates or pronounced adverse effects, and there remains a lack of ideal long-term therapeutic options in clinical practice (9)

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GR is a flavo-protein oxidoreductase ubiquitously present in both prokaryotes and eukaryotes (Romeo-Puertas et al., 2006)

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However, their dysregulation can exacerbate inflammation and tissue damage in ARDS ( Given the central role of oxidative stress and lipid peroxidation in ARDS, targeting ferroptosis represents a promising therapeutic strategy ( 2 Ferroptosis in infection and ARDS development Cell death pathways play critical roles in immune homeostasis, infection defense, and inflammation resolution

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Administered intravenously or as an injection, glutathione inhibits tyrosinase the enzyme responsible for melanin production reducing pigmentation and brightening skin tone

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