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Therefore, FSP1 may represent a promising target for cancer therapy (64)

The introduction of the NO-synthase inhibitor L-NAME (1 mol/L) into the perfusing solution 20 min before the acetylcholine reduced the vasodilator responses of aortic rings to acetylcholine in 9.41 times ( p = 0.003) (Figure 5C)

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In addition, in the xenograft model, ultra-small silica nanoparticles were shown to induce ferroptosis by increasing the transport and accumulation of iron in cells and inhibit tumor growth [206, 207]

Consequently, therapeutic strategies that either inhibit or activate glucagon are being actively researched in clinical settings [104]

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