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Crohns disease typically affects the ileum, the last portion of the small intestine, which absorbs vitamin B12

Recent evidence shows that gut microbiota plays a significant role in maintaining homeostasis and regulating the MGBA, which influences the neural and GI responses to RT ( 3.7.2 MGBA disruption by RT Using RT in the abdomino-pelvic region can cause gut dysbiosis, due to the reduction of Firmicutes and Bacteroidetes species accompanied by the surge in Proteobacteria species

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Combination Approaches These approaches are not mutually exclusive

Third, there is a big difference between biochemical B12 deficiency and B12 deficiency symptoms

These results provide a novel therapeutic approach to ICH