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Inhibitors of GABAA receptors, specifically picrotoxin and bicuculline, completely abrogated the ability of both methanolic and aqueous extracts from WS roots to cause depolarization in gonadotropin releasing hormone neurons in mice

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Patients taking any prescription medications must consult their prescribing physician before initiating berberine supplementation to avoid severe adverse interactions

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Am J Geriatr Psychiatry 2004