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Side effects are uncommon and typically mild, such as temporary redness or irritation with topical use or slight discomfort at the injection site

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doi: 10.1016/j.nut.2013.12.009 22 WangYWuYWangYFuAGongLLiWet al

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Seventy percent of study volunteers showed collagen increases compared to untreated controls a response rate significantly higher than that achieved by either comparator compound, both of which are considered first-line clinical options for photoaged skin