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Because c-Myc mediated miR-23a and miR-23b repression, overexpression of c-MYC can upregulate GLS, and therefore promote glutaminolysis (Gao et al., 2009) (Figure 2)

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N., Shen, Y., Brodsky, J

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2.1.2.2 Regulatory approvals - Expedite the review process for pediatric indications of novel anti-obesity pharmacotherapies