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These differences highlight the need for tailored therapeutic strategies, EHS may benefit from early anti-pyroptotic/anti-necroptotic agents, while CHS requires prioritized gut barrier protection and anti-apoptotic interventions

Typically, these guidelines suggest initiating intravenous immunoglobulin (IVIG) therapy as the primary treatment for MIS-C, drawing on the experience gained from IVIG usage in Kawasaki disease [26]

Important reminder that obesity management is not one-size-fits-all

This may come in the form of using combinations of NuSHs that have more favorable effects on body composition or using combinations of NuSH-based medications with MAPi-based medications

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