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The powder may have degraded before reconstitution, or the water temperature was too extreme

7: 267274 Hitoshi Masaki

11 Lack of supply There is a shortage of both semaglutide and tirzepatide due to their unprecedented demand, with both now listed in the FDA Drug Shortages database, allowing for compounded versions to be made (although that does not make such versions FDA-approved)

Four years later, Novo Nordisk, a Danish pharmaceutical company began developing a once-weekly semaglutide injection intended for the treatment of Type 2 Diabetes and called the new drug Ozempic

Med Lett Drugs Ther (2022) 64(1654):1057