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Through its ability to block NOTCH1 maturation, CHAC1/BOTCH was identified as Neuroprotective Gene 7 (NPG7) due to its protective effects in neuronal contexts

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Leis Ayres E, Costa A, Eberlin S, Piatto Clerici S (2015) Estudo ex vivo para avaliao da atividade clareadora do Pycnogenol aps exposio radiao ultravioleta, infravermelha e luz visvel

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