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Indeed, among female smokers, two years of smoking cessation reduced cardiovascular mortality by 24% [49], and smoking cessation after myocardial infarction has been reported to reduce mortality by 2050% compared with that in continuing smokers [50]

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doi: 10.1038/s41531-025-00995-0, 139 ZhangN.YuX.SongL.XiaoZ.XieJ.XuH

Analgesic and sedative effects of melatonin in temporomandibular disorders: a double-blind, randomized, parallel-group, placebo-controlled study

If there is concern about TMAO risk, clinicians can discuss the limited evidence, consider monitoring and prefer conservative dosing