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Therefore, focus has been drawn towards targeting the glutathione antioxidant system in tumor cells as a therapeutic approach using drugs to target glutathione directly, indirectly, or by using glutathione-based prodrugs (Figure 4) [15]

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Contraindications: May have a deleterious effect on the injured or failing heart (by increasing myocardial oxygen requirements while decreasing effective coronary perfusion) Side Effects: CNS : Nervousness, Headache Dizziness Cardiovascular : Tachycardia, ventricular arrhythmias Palpitations Angina Hyper- or hypo-tension Adams-Stokes attacks Pulmonary edema Pharmacokinetics: Isoproterenol is readily absorbed when given parenterally or as an aerosol

Normal Saline (200 ml): Rehydrates and aids nutrient delivery