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Similar to the dietary causes of homocystinuria, hyperhomocysteinemia can result from deficiencies in vitamin B6, vitamin B12, and folate

involved administering 500 mg/day of GSH in two divided doses to the study population, the difference being the use of a buccal lozenge (instead of oral capsules) in the latter study to enhance systemic absorption of glutathione [10,11]

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Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG: Genetically altered mice to evaluate glutathione homeostasis in health and disease

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