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Materials and methods Study participants Men and women aged between 18 and 80 years diagnosed with NAFLD by ultrasound who had an increased serum level of alanine transaminase (ALT) were recruited from the Gastroenterology Clinic and Radiology Center of Shahid Beheshti Hospital, Kashan University of Medical Sciences

Clinical trials are needed to confirm safety and dosing

Storage & Handling Storage Lyophilized vials: store at 20C , sealed, protected from light and moisture

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Degraded in GI tract Hepatic first-pass processing Absorption varies by formulation Glutathione Injection Bypasses gastrointestinal processing entirely

Furthermore, cellular antioxidant capability is also decreased by suppressed GPx4 expression (e.g., RSL3), which results in lipid peroxidation and ferroptosis [76]