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What contraindications are there for using a GLP-1 agonist

While effective for short-term weight loss, many users experience nausea, bloating, fatigue, and other digestive issues in the early months of treatment

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The 0.25 mg dose is primarily a stepping stone

Zeng C, Wang S, Gu H, Chen F, Wang Z, Li J

Similarly, continuous subcutaneous administration of native GIP for 6 days in men with type 1 diabetes increased hepatic steatosis but had little impact on a wide range of metabolic variables, including markers of bone resorption, biomarkers of inflammation, and body weight [65]