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Single-cell RNA-sequencing, metabolomic, proteomic, and transcriptomic analyses, together with immunoprecipitation, mass spectrometry, GST-pulldown assays, oxygen consumption rate assays, and other methods, were used to reveal the mechanism of PRMT1 in renal injury caused by CaOx crystals

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Additionally, AQP9 deficiency leads to impaired glycogen synthesis, evidenced by increased levels of phosphorylated glycogen synthase (GS)

Chemotherapy and radiation therapy can damage intestinal cells, leading to glutamine deficiency

Glutathione is made from the sulfur-containing amino acid cysteine

Custom-designed siRNA library plates and individual siRNAs were obtained from the siGenome Human siRNA catalogue (Dharmacon, Horizon Discovery)