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Patient-specific (503A) compounding still has a narrow, legitimate role for documented clinical needs (for example, a true allergy to an inactive ingredient), but it cannot legally replicate the scale or economics of the boom years
Tirzepatide also reduces liver fat, with studies showing meaningful improvements, but the magnitude does not approach what retatrutide achieves
doi: 10.1016/j.phrs.2022.106320 35
Some pharmacies are still getting compounded medications
While originally developed for blood sugar management, GLP-1 and GIP therapies are now commonly used under medical supervision to support metabolic health, weight management, and body composition in individuals who meet appropriate criteria