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In a pilot study of 39 patients with IIH and BMI greater than 30 kg/m 2 , patients treated with semaglutide or liraglutide in addition to counselling on diet and exercise achieved significantly greater weight loss (12%) after 6 months than those offered counselling alone (2.8%) (10)

The Phase 2 data showing 24.2% body weight loss in 48 weeks through a novel triple-agonist mechanism is unprecedented

Direct answer: Tirzepatide targets two hormone pathways, which may create stronger appetite control for some people

Case report 2.1

Avoid shaking the vial, as peptides are fragile proteins

Two reasons: membership fees and dose-escalation pricing