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S-glutathionylation of the p65 and p50 subunits of NF-B inhibits NF-B binding to the DNA (256, 260), while S-glutathionylation of the inhibitory kappa B kinase beta subunit represses NF-B transactivation (219, 275)

RNS, reactive nitrogen species

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Conversely, normal oxidative-stress biomarkers do not rule out atherosclerosis, high blood pressure, inherited cardiovascular risk, structural heart disease, or other health concerns

doi: 10.1016/j.jaci.2019.04.029 112 SliekerRCvan ItersonMLuijkRBeekmanMZhernakovaDVMoedMHet al