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If you boost GABA (such as with benzos), the brain will push the other way and actually reduce naturally-occurring GABA function

and (3) ubiquinol as in reduced state

116 ShiG

Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S (2011) Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis

Comprehensive computational exome sequencing analysis also revealed a number of genes, six of which ( SETD1A , CUL1 , XPO7 , GRIA3 , GRIN2A , and RB1CC1 ) had odds ratios higher than ten, with their rare mutations markedly increasing the risk for schizophrenia (Nakamura and Takata, 2023)

It increases the availability of free fatty acids for energy, improving body composition even in calorie-controlled phases