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ADVERSE REACTIONS : Adverse reactions reported in 5% of patients treated with JANUVIA and more commonly than in patients treated with placebo are: upper respiratory tract infection, nasopharyngitis and headache

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After the original oxycodone composition-of-matter patent expired, Purdue listed formulation patents covering the abuse-deterrent matrix, extending Orange Book protection and creating a new barrier to generic entry requiring bioequivalence to the reformulated product, not the original

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