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Transdermal estrogen also carries additional benefits independent of GLP-1 compatibility

In an embryofetal development study in pregnant cynomolgus monkeys, subcutaneous doses of 0.015, 0.075, and 0.15 mg/kg twice weekly (0.4-, 2-, and 6-fold the MRHD) were administered throughout organogenesis, from Gestation Day 16 to 50

Its important to note that one should never use this method on their own

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This observation is the conceptual anchor of an entire branch of supplementation research the research into glutathione precursors, NAC, and the cysteine pool