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They revealed an inhibitory microcircuit within the LS projecting from the dorsal LS (dLS) to the ventral LS (vLS): GLP-1R neurons in the dLS directly inhibited neurons expressing estrogen receptor 1 (Esr1) in the vLS through GABAergic synapses

Large majorities of Republicans (73%) and MAGA supporters (83%) say it is likely that the Trump administration will lower drug prices for people like them, while far fewer independents (33%) and just one in 10 Democrats (9%) say that it is likely

The algorithms analyzed by TruAge include first- (Horvath and Hannum), second- (phenoAge, systemsAge, OMICAge, and GrimAge), and third-generation clocks (DunedinPACE)

Despite their current dominance, GLP-1R agonists are not the only contributors to future growth

Mechanism: Targets GLP-1, GIP, and glucagon receptors