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Can be used as monotherapy or in combination with other diabetes medications including metformin, sulfonylureas, SGLT2 inhibitors, and insulin

Ann N Y Acad Sci 2009;1170:98-101

All patients were aged at least 45 years, had overweight or obesity, had ASCVD (prior heart attack, stroke or peripheral artery disease) and did not have diabetes

NIAAA Klausen MK, Justesen SK, Pedersen JN, et al

If your tummy feels strange, take a deep breath and try to relax

Recent studies have highlighted the central roles of metabolic regulators AMP-activated protein kinase and Peroxisome proliferator-activated receptor gamma and the histone methyltransferase Enhancer of zeste homolog 2 in modulating corpus luteum function