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Agonistes du rcepteur du GLP-1 et sant cardiomtabolique Les maladies cardiovasculaires, rnales et mtaboliques coexistent souvent et reprsentent une charge de morbidit considrable lchelle mondiale

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Trial Evidence Supporting Approval The approval is based on interim data from Part 1 of the phase 3 ESSENCE trial, which enrolled 800 adults with MASH and stage F2F3 fibrosis

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Prostaglandins also help maintain renal perfusion by dilating the afferent arteriole, particularly in patients with intravascular volume depletion (eg, congestive heart failure, diarrhea, excessive diuresis) or chronic kidney disease